Sam Rodriques

Sam Rodriques received his undergraduate degree in physics from Haverford College, Pennsylvania. He spent two years at the University of Cambridge, studying Applied Mathematics and Theoretical Physics during the first year, and researching computational neuroscience in the Computational and Biological Learning Lab during the second. He then completed a Ph.D. in Physics at MIT, developing tools towards achieving a broad understanding of the brain, its functions, and its pathologies. He then went on to accept a group leader position at the Francis Crick Institute.

Publications

Combinatorial protein barcodes enable self-correcting neuron tracing with nanoscale molecular context

bioRxiv | 2025

Park SY*, Sheridan A*, An B, Jarvis E, Lyudchik J, Patton W, Axup JY, Chan SW, Damstra HGJ, Leible D, Leung KS, Magno CA, Meeran A, Michalska JM, Rieger F, Wang C, Wu M, Church GM, Funke J, Huffman T, Leeper KGC**, Truckenbrodt S**, Winnubst J**, Kornfeld JMR, Boyden ES+, Rodriques SG***, Payne AC+*** (2025) Combinatorial protein barcodes enable self-correcting neuron tracing with nanoscale molecular context, bioRxiv 2025.09.26.678648, doi: 10.1101/2025.09.26.678648. (*, contributed equally; **, contributed equally; ***, contributed equally; +, co-corresponding)

RNA timestamps identify the age of single molecules in RNA sequencing

Nature Biotechnology | 2020

Samuel G. Rodriques*, Linlin M. Chen*, Sophia Liu, Ellen D. Zhong, Joseph R. Scherrer, Edward S. Boyden**, Fei Chen** (2020) RNA timestamps identify the age of single molecules in RNA sequencing, Nature Biotechnology 39:320–325. (*, equal contribution, **, co-corresponding)