Aimei Yang
Aimei is a research scientist spearheading several molecular engineering projects in the lab, ranging from genomic search strategies for novel molecules, to high-throughput screening methods for creating new molecular tools.
Publications
Oxytocin-dependent reopening of a social reward learning critical period with MDMA
Nature | 2019Nardou R, Lewis EM, Rothhaas R, Xu R, Yang A, Boyden E, Dölen G (2019) Oxytocin-dependent reopening of a social reward learning critical period with MDMA, Nature 569(7754):116-120.
Melanopsin for precise optogenetic activation of astrocyte-neuron networks
Glia | 2019Sara Mederos, Alicia Hernández‐Vivanco, Jorge Ramírez‐Franco, Mario Martín‐Fernández, Marta Navarrete, Aimei Yang, Edward S. Boyden, Gertrudis Perea (2019) Melanopsin for precise optogenetic activation of astrocyte‐neuron networks, Glia 67(5):915-934.
Multidimensional screening yields channelrhodopsin variants having improved photocurrent and order-of-magnitude reductions in calcium and proton currents
Journal of Biological Chemistry | 2019Cho YK, Park D*, Yang A*, Chen F, Chuong AS, Klapoetke NC, Boyden ES (2019) Multidimensional screening yields channelrhodopsin variants having improved photocurrent and order-of-magnitude reductions in calcium and proton currents, Journal of Biological Chemistry 294(11):3806-3821. (*, equal contribution)
Dopamine Neuron-Specific Optogenetic Stimulation in Rhesus Macaques
Cell | 2016Stauffer WR, Lak A, Yang A, Borel M, Paulsen O, Boyden ES, Schultz W (2016) Dopamine Neuron-Specific Optogenetic Stimulation in Rhesus Macaques, Cell 166(6):1564-1571
Stress Enables Reinforcement-Elicited Serotonergic Consolidation of Fear Memory
Biological Psychiatry | 2015Baratta MV, Kodandaramaiah SB, Monahan PE, Yao J, Weber MD, Lin PA, Gisabella B, Petrossian N, Amat J, Kim K, Yang A, Forest CR, Boyden ES, Goosens KA (2015) Stress Enables Reinforcement-Elicited Serotonergic Consolidation of Fear Memory, Biological Psychiatry 79(10):814-22.
Microchip amplifier for in vitro, in vivo, and automated whole-cell patch-clamp recording
Journal of Neurophysiology | 2014Harrison R.R., Kolb I., Kodandaramaiah S.B., Chubykin A.A., Yang A., Bear M.F., Boyden E.S.*, Forest C.* (2014) Microchip amplifier for in vitro, in vivo, and automated whole-cell patch-clamp recording, Journal of Neurophysiology 113(4):1275-82. (*, equal contribution)
Optogenetic astrocyte activation modulates response selectivity of visual cortex neurons in vivo
Nature Communications | 2014Perea, G., Yang, A., Boyden, E. S., Sur, M. (2014) Optogenetic astrocyte activation modulates response selectivity of visual cortex neurons in vivo, Nature Communications 5:3262.
Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement
PLoS One | 2012Kim K.M., Baratta M.V., Yang A., Lee D., Boyden E.S.*, Fiorillo C.D.* (2012) Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement, PLoS One 7(4):e33612. (* co-corresponding authors)
A high-light sensitivity optical neural silencer: development, and application to optogenetic control of nonhuman primate cortex
Frontiers in Systems Neuroscience | 2011Han, X.*, Chow, B. Y.*, Zhou, H., Klapoetke, N. C., Chuong, A., Rajimehr, R., Yang, A., Baratta, M. V., Winkle, J., Desimone, R., Boyden, E. S. (2011) A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex, Frontiers in Systems Neuroscience 5:18. (* co-first authors)
Mapping Brain Networks in Awake Mice Using Combined Optical Neural Control and fMRI
Journal of Neurophysiology | 2010Desai M., Kahn I., Knoblich U., Bernstein J., Atallah H., Yang A., Kopell, N., Buckner R.L., Graybiel A. M., Moore C. I.*, and Boyden E. S.* (2011) Mapping Brain Networks in Awake Mice Using Combined Optical Neural Control and fMRI, Journal of Neurophysiology 105(3):1393-405. (* co-corresponding authors)