Pablo Valdes Quevedo

Pablo is originally from Central America, and moved to the USA to pursue his training as a physician scientist. He received his MD from Dartmouth Medical School, and his PhD from Thayer School of Engineering at the combined MD/PhD program at Dartmouth College . His research was in developing optical imaging technologies for neurosurgical guidance in the laboratory of Drs. David Roberts and Keith Paulsen. He then went on to become a Neurosurgical resident at the Harvard Medical School Department of Neurosurgery at Brigham and Women’s/Boston Children’s Hospitals, working on imaging technologies for improving our understanding and treatment of gliomas.

Publications

Improved immunostaining of nanostructures and cells in human brain specimens through expansion-mediated protein decrowding

Science Translational Medicine | 2024

Valdes PA, Yu CJ*, Aronson J*, Ghosh D, Zhao Y, An B, Bernstock JD, Bhere D, Felicella MM, Viapiano MS, Shah K, Chiocca EA**, Boyden ES** (2024) Improved immunostaining of nanostructures and cells in human brain specimens through expansion-mediated protein decrowding, Science Translational Medicine 16(732):eabo0049. (*, contributed equally; **, contributed equally)

Spatial multiplexing of fluorescent reporters for imaging signaling network dynamics

Cell | 2020

Changyang Linghu*, Shannon L. Johnson*, Pablo A. Valdes, Or A. Shemesh, Won Min Park, Demian Park, Kiryl D. Piatkevich, Asmamaw T. Wassie, Yixi Liu, Bobae An, Stephanie A. Barnes, Orhan T. Celiker, Chun-Chen Yao, Chih-Chieh (Jay) Yu, Ru Wang, Katarzyna P. Adamala, Mark F. Bear, Amy E. Keating and Edward S. Boyden (2020) Spatial multiplexing of fluorescent reporters for imaging signaling network dynamics, Cell 183(6):1682-1698. (*, equal contribution)